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Untreated, it can lead to complications and death. [67] Clinical manifestations of syphilis include the ulceration of the uro-genital tract, mouth or rectum; if left untreated the symptoms worsen. In recent years, the prevalence of syphilis has declined in Western Europe, but it has increased in Eastern Europe (former Soviet states).
This can be caused by the formation of scar tissue due to one or more episodes of PID, and can lead to tubal blockage. Both of these increase the risk of the inability to get pregnant, [27] and 1% results in an ectopic pregnancy. [40] Chronic pelvic/abdominal pain develops post PID 40% of the time. [40]
Phase variation is similar to antigenic variation, but instead of changes at the genetic level altering the composition of molecules, these genetic changes result in the activation or deactivation of a gene. [9] Phase variation most often arises from a frameshift in the expressed gene. [9]
Reproductive tract infection (RTI) are infections that affect the reproductive tract, which is part of the reproductive system.For females, reproductive tract infections can affect the upper reproductive tract (fallopian tubes, ovary and uterus) and the lower reproductive tract (vagina, cervix and vulva); for males these infections affect the penis, testicles, urethra or the vas deferens.
An average cancer of the breast or colon can have about 60 to 70 protein altering mutations, of which about 3 or 4 may be "driver" mutations, and the remaining ones may be "passenger" mutations [17] Any genetic or epigenetic lesion increasing the mutation rate will have as a consequence an increase in the acquisition of new mutations ...
HIV is a retrovirus, which means it can integrate its genetic material into your cells’ DNA. As cells reproduce, the HIV DNA inside replicates fast and makes mistakes, creating mutations that ...
If left untreated, chlamydia in men can spread to the testicles causing epididymitis, which in rare cases can lead to sterility if not treated. [15] Chlamydia is also a potential cause of prostatic inflammation in men, although the exact relevance in prostatitis is difficult to ascertain due to possible contamination from urethritis. [19]
Untreated gonorrhea can lead to major complications, such as: Infertility in women. Gonorrhea can spread into the uterus and fallopian tubes, causing pelvic inflammatory disease (PID). PID can result in scarring of the tubes, greater risk of pregnancy complications and infertility, and can be fatal, particularly in the immunocompromised.