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Weber's syndrome, also known as midbrain stroke syndrome or superior alternating hemiplegia, is a form of stroke that affects the medial portion of the midbrain. It involves oculomotor fascicles in the interpeduncular cisterns and cerebral peduncle so it characterizes the presence of an ipsilateral lower motor neuron type oculomotor nerve palsy and contralateral hemiparesis or hemiplegia.
Brain anatomy – forebrain, midbrain, hindbrain. The cerebral peduncles each form a lobe ventrally of the tegmentum, on either side of the midline. Beyond the midbrain, between the lobes, is the interpeduncular fossa , which is a cistern filled with cerebrospinal fluid [ citation needed ] .
Brainstem stroke syndrome can cause a range of impairments including locked-in syndrome. Duret haemorrhages are areas of bleeding in the midbrain and upper pons due to a downward traumatic displacement of the brainstem. [11]: 842 Cysts known as syrinxes can affect the brainstem, in a condition, called syringobulbia. These fluid-filled cavities ...
Cerebral infarction, also known as an ischemic stroke, is the pathologic process that results in an area of necrotic tissue in the brain (cerebral infarct). [1] In mid to high income countries, a stroke is the main reason for disability among people and the 2nd cause of death. [2]
Neurobiologists have often had great difficulty distinguishing the VTA in humans and other primate brains from the substantia nigra (SN) and surrounding nuclei. Originally, the ventral tegmental area was designated as a ‘nucleus’, but over time ‘area’ became the more appropriate term used because of the heterogeneous cytoarchitectonic features of the region and the lack of clear ...
Stroke occurs when blood flow to the brain is blocked or there’s sudden bleeding in the brain. Unless treated quickly, it can lead to lasting brain damage, long-term disability or death.
The periaqueductal gray (PAG), also known as the central gray, is a brain region that plays a critical role in autonomic function, motivated behavior and behavioural responses to threatening stimuli. [1] [2] PAG is also the primary control center for descending pain modulation. It has enkephalin-producing cells that suppress pain.
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