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After injection, microcrystals gradually release insulin over a period of approximately 24 hours. [81] This insulin works by facilitating the absorption of glucose by body tissues and reducing glucose production by the liver. [81] Insulin glargine was patented, although the patent expired in most countries in 2014.
Insulin is a peptide hormone containing two chains cross-linked by disulfide bridges. Insulin (/ ˈ ɪ n. sj ʊ. l ɪ n /, [5] [6] from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene. It is the main anabolic hormone of the body. [7]
I think "Certain insulin brands can also have differing names regionally, such as how Novolog is called Novorapid outside of the United States. Brands may also be commonly referred to with different names" is unsourced. Ping when done, please. History6042😊 (Contact me) 21:15, 24 February 2025 (UTC)
NPH insulin is cloudy and has an onset of 1–3 hours. Its peak is 6–8 hours and its duration is up to 24 hours. [9]It has an intermediate duration of action, meaning longer than that of regular and rapid-acting insulin, and shorter than long acting insulins (ultralente, glargine or detemir).
Examples of intermediate-acting insulins (peak 4–10 hours) are: Isophane insulin, neutral protamine Hagedorn (NPH) (Humulin N, Novolin N) Insulin zinc (Lente) Examples of long-acting insulins (duration 24 hours, often without peak) are: Extended insulin zinc insulin (Ultralente) Insulin glargine (Lantus) Insulin detemir (Levemir)
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