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Insulin detemir is a long-acting modified form of medical insulin used to treat both type 1 and type 2 diabetes. [75] It is administered through subcutaneous injection. Its effects last for up to 24 hours. [75] Common side effects include (hypoglycemia, allergic reactions, pain at the injection site, and weight gain. [75]
Novo Nordisk created insulin detemir and markets it under the trade name Levemir as a long-lasting insulin analogue for maintaining the basal level of insulin. [1] [5] The basal level of insulin may be maintained for up to 20 hours, but the time is affected by the size of the injected dose.
Insulin glargine sold under the brand name Lantus among others is a long-acting modified form of medical insulin, used in the management of type 1 and type 2 diabetes. [7] It is injected just under the skin . [ 7 ]
Another advantage of long-acting insulins is that the basal component of an insulin regimen (providing a minimum level of insulin throughout the day) can be decoupled from the prandial or bolus component (providing mealtime coverage via ultra-short-acting insulins), while regimens using NPH and regular insulin have the disadvantage that any ...
Insulin degludec is a modified insulin that has one single amino acid deleted in comparison to human insulin, and is conjugated to hexadecanedioic acid via gamma-L-glutamyl spacer at the amino acid lysine at position B29. It is included on the World Health Organization's List of Essential Medicines [11] as an equivalent to insulin glargine.
The latest clinical trial results from Eli Lilly show the drug manufacturer's once-weekly insulin injection is just as effective as daily insulin shots for managing A1C levels in diabetes. Experts ...
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