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The most common adverse effects noted for second-generation agents include drowsiness, fatigue, headache, nausea and dry mouth. [4] Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk for cognitive decline and dementia in older people. [8] [9]
Drug interactions aren’t common with Zyrtec, according to the FDA, Dr. Brooks says you’ll want to be careful about using other medications that can cause drowsiness at the same time. Claritin
A single bedtime dose after the last feeding of the day may minimize the harmful effects of the medication on the baby and the milk supply. Still, non-sedating antihistamines are preferred. [37] Paradoxical reactions to diphenhydramine have been documented, particularly in children, and it may cause excitation instead of sedation. [38]
Among second-generation antihistamines, cetirizine is more likely than fexofenadine and loratadine to cause drowsiness. [7] Use in pregnancy appears safe, but use during breastfeeding is not recommended. [8] The medication works by blocking histamine H 1 receptors, mostly outside the brain. [6] Cetirizine can be used for paediatric patients.
Levocetirizine, sold under the brand name Xyzal, among others, is a second-generation antihistamine used for the treatment of allergic rhinitis (hay fever) and long-term hives of unclear cause. [3] It is less sedating than older antihistamines. [4] It is taken by mouth. [3] Common side effects include sleepiness, dry mouth, cough, vomiting, and ...
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