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Local anesthesia, in a strict sense, is anesthesia of a small part of the body such as a tooth or an area of skin. Regional anesthesia is aimed at anesthetizing a larger part of the body such as a leg or arm. Conduction anesthesia encompasses a great variety of local and regional anesthetic techniques.
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
This is a list of local anesthetic agents. Not all of these drugs are still used in clinical practice and in research. Some are primarily of historical interest.
Tumescent anesthesia is a surgical technique for delivery of local anesthesia. It also makes the target tissue firm and turgid from absorbed water, which can aid certain procedures. It was originally devised for use in liposuction, but has since been applied to other surgical situations, including plastic surgery, burn care, and vascular surgery.
A topical anesthetic is a local anesthetic that is used to numb the surface of a body part. They can be used to numb any area of the skin as well as the front of the eyeball, the inside of the nose, ear or throat, the anus and the genital area. [1] Topical anesthetics are available in creams, ointments, aerosols, sprays, lotions, and jellies.
Local anesthetic injections are given in specific areas of the mouth, rather than the whole body. Although several different medications are available, the most commonly used local anesthetic to prevent pain in the area around a tooth is lidocaine (also called xylocaine or lignocaine). Lidocaine's half-life in the body is about 1.5–2 hours. [2]
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It is the most commonly used local anesthetic in epidural anesthesia during labor, as well as in postoperative pain management. [14] Liposomal formulations of bupivacaine (brand name EXPAREL) have not shown clinical benefit compared to plain bupivacaine when used in traditional perineural injections, [ 15 ] although some industry-funded studies ...