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The results were measured as mean monthly migraine days in months 4, 5, and 6. At baseline the patients experienced between 4 and 14 migraine days per month with an average of 8.3. The medication significantly reduced the number of migraine days per month by 3.2 in the 70-mg group and 3.7 in the 140-mg group, versus 1.8 in the placebo (0-mg) group.
In two studies involving 1,784 participants who had migraines between 4 and 14 days a month, those treated with galcanezumab had four or five fewer days with migraines per month, compared with two to three fewer days for participants on a placebo injection. [3] Trial three enrolled participants with a history of chronic migraine headaches. [10]
Physiotherapy, massage and relaxation, and chiropractic manipulation might be as effective as propranolol or topiramate in the prevention of migraine headaches; however, the research had some problems with methodology. [89] [90] Another review, however, found evidence to support spinal manipulation to be poor and insufficient to support its use ...
Fremanezumab, sold under the brand name Ajovy, is a medication used to prevent migraines in adults. [8] [6] It is given by injection under the skin.[8] [6]The most common side effect is pain and redness at the site of injection. [8]
Compounded semaglutide is a more affordable option, with monthly plans starting at $199 for those who qualify. ... There are a few injection sites you can use to inject subcutaneous semaglutide ...
Trial 1 enrolled participants with a history of episodic migraine headaches and Trial 2 enrolled participants with chronic migraine headaches. [10] Participants were assigned to receive one of two doses of eptinezumab or placebo injections every three months for a total of twelve months in Trial 1, and for a total of 6 months in Trial 2. [10]
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