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Glucocorticoid therapy in CAH impairs working memory and causes brain changes, including white matter hyperintensities, suggesting a reduction in white matter structural integrity. [12] Cognitive impairment, when observed, has occasionally been attributed to hypoglycemia and electrolyte imbalances at the initial presentation. [ 12 ]
Late onset congenital adrenal hyperplasia (LOCAH), also known as nonclassic congenital adrenal hyperplasia (NCCAH or NCAH), is a milder form of congenital adrenal hyperplasia (CAH), [1] a group of autosomal recessive disorders characterized by impaired cortisol synthesis that leads to variable degrees of postnatal androgen excess.
Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. [6] It is recommended to be used together with dietary changes, exercise, and weight loss. [6] It is taken orally (by mouth). [6]
Simvastatin is contraindicated with pregnancy, breastfeeding, and liver disease. [16] Pregnancy must be avoided while on simvastatin due to potentially severe birth defects. Patients cannot breastfeed while on simvastatin due to potentially disrupting the infant's lipid metabolism. [17]
Some statins may also alter the concentrations of other medications, such as warfarin or digoxin, leading to alterations in effect or a requirement for clinical monitoring. [56] The increase in digoxin levels due to atorvastatin is a 1.2 fold elevation in the area under the curve (AUC), resulting in a minor
Changes to your daily routine that affect your sleep schedule. ... Pregnancy or having a new baby. High levels of psychological stress. ... If they don’t help you get to sleep, they’ll at ...
Crystal Methamphetamine is an example of a recreational drug that can have serious negative consequences on fetal memory development if used during pregnancy. Similarly to nutritional intake, drugs consumed by the mother during pregnancy can affect the brain development of her fetus.
Statins are usually used to lower blood cholesterol levels and reduce risk for illnesses related to atherosclerosis, with a varying degree of effect depending on underlying risk factors and history of cardiovascular disease. [16]