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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Remember, tadalafil 5-milligram side effects tend to be less severe than those experienced with 10- or 20-milligram dosages. Your provider may recommend adjusting your Cialis dosage if you’re ...

  3. Thin-film drug delivery - Wikipedia

    en.wikipedia.org/wiki/Thin-film_drug_delivery

    Similar in size, shape and thickness to a postage stamp, thin-film strips are typically designed for oral administration, with the user placing the strip on or under the tongue (sublingual) or along the inside of the cheek (buccal). These drug delivery options allow the medication to bypass the first pass metabolism thereby making the ...

  4. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    Like other ED medications, Cialis and generic tadalafil can cause side effects. Most side effects of daily-use Cialis are identical to those that can occur when Cialis is used as needed, although ...

  5. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    If you struggle with ED, drugs like Viagra®, sildenafil, tadalafil, and other FDA-approved medications could help with your performance. But if you’re not prescribed one of these meds, taking ...

  6. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]

  7. Sublingual administration - Wikipedia

    en.wikipedia.org/wiki/Sublingual_administration

    Sublingual tablets—tablets which easily melt in the mouth, dissolve rapidly and with little or no residue. Nitroglycerine tablets are an example, the anti-emetic ondansetron is another. Sublingual strips—similar to tablets in that they easily melt in the mouth and dissolve rapidly.

  8. Oral administration - Wikipedia

    en.wikipedia.org/wiki/Oral_administration

    Oral administration can be easier and less painful than other routes of administration, such as injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may ...

  9. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Tadalafil. The active ingredient in Cialis, tadalafil is a long-lasting medication that can provide relief from ED for up to 36 hours. Vardenafil. The active ingredient in Levitra, vardenafil can ...