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In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [61] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
Rifampin rapidly kills fast-dividing bacilli strains as well as "persisters" cells, which remain biologically inactive for long periods of time that allow them to evade antibiotic activity. [7] In addition, rifabutin and rifapentine have both been used against tuberculosis acquired in HIV-positive patients.
In non-resistant TB, rifampin binds the beta subunit of RNA polymerase and disrupts transcription elongation. Mutation in the rpoB gene changes the sequence of amino acids and eventual conformation, or arrangement, of the beta subunit. In this case, rifampin can no longer bind or prevent transcription, and the bacterium is resistant. [19] [20]
Thuận Thành is a district-level town (thị xã) of Bắc Ninh province in the Red River Delta region of Vietnam. As of 2022 the town had a population of 199,577. [1] The district covers an area of 117.83 km². The town seat lies at Hồ.
Bùi Tằng Việt was born in 1922 in Việt Yên, Bắc Giang to a scholar who came from Song Hồ commune, Thuận Thành, Bắc Ninh.Graduated from the Thăng Long High School in Hà Nội, Bùi Tằng Việt began his career as a writer and translator for the Tân dân xã publishing house which was owned by Vũ Đình Long, from that time he chose the pen name Hoàng Cầm which is the ...
Phan Huỳnh Điểu (11 November 1924, in Đà Nẵng – 29 June 2015 [1]) was a Vietnamese composer. [2] He composed the military anthem vi:Đoàn Vệ quốc quân (1945), and was a recipient of the Hồ Chí Minh Prize in 2000.
Rifapentine, sold under the brand name Priftin, is an antibiotic used in the treatment of tuberculosis. [2] In active tuberculosis it is used together with other antituberculosis medications. [2]
It contains ethambutol, isoniazid, and rifampicin. [1] It is used either along or with other anti-tuberculosis medication. [1] It is taken by mouth. [1] Side effects are those of the underlying medications. [1] Use may not be suitable in children. [1] It is on the World Health Organization's List of Essential Medicines. [2]