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Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
Corticosteroid-induced lipodystrophy (CIL) is a condition of abnormal fat deposition caused by corticosteroid medications. [1] Fat accumulates in the facial area ("moon face"), dorsocervical region ("buffalo hump"), and abdominal area ("pot belly" or "beer belly"), whereas the thickness of subcutaneous fat in the limbs is decreased. [1]
Synthetic pharmaceutical drugs with corticosteroid-like effects are used in a variety of conditions, ranging from hematological neoplasms [3] to brain tumors or skin diseases. Dexamethasone and its derivatives are almost pure glucocorticoids, while prednisone and its derivatives have some mineralocorticoid action in addition to the ...
When you eat ultra-processed foods, you starve your microbiome of the nutrients it needs from whole, fresh food. "This can cause leaky gut syndrome and increase inflammation and oxidative stress ...
Weight loss is a famous side effect of Ozempic, the Type 2 diabetes drug, but patients often find they must avoid certain foods on the medication. It’s a similar story with Wegovy , the form of ...
Since Wegovy also slows digestion, this can end up piling onto the gastrointestinal side effects. Plus, these foods can be calorie-dense without filling you up too much, so you might eat more than ...
Adrenal insufficiency (if used for long time and stopped suddenly without a taper) Muscle and tendon breakdown (proteolysis), weakness, reduced muscle mass and repair [51] [31] Expansion of malar fat pads and dilation of small blood vessels in skin; Lipomatosis within the epidural space [52] Excitatory effect on central nervous system (euphoria ...
Auxiliary label stating the medication must be swallowed whole, without crushing or chewing. Auxiliary labels stating "take with food or milk" and "do not take with aspirin" Auxiliary labels are small stickers consisting of one or more lines of text intended to enhance patient knowledge, with or without a pictogram. The directions for use ...