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Printable version; Page information; ... This diagram uses embedded text that can be easily translated using a text editor. ... Mevalonate pathway: Width: 744.09448819:
A third mevalonate pathway variant found in Thermoplasma acidophilum, phosphorylates mevalonate at the 3-OH position followed by phosphorylation at the 5-OH position. The resulting metabolite, mevalonate-3,5-bisphosphate, is decarboxylated to IP, and finally phosphorylated to yield IPP (Archaeal Mevalonate Pathway II). [6] [7]
Mevalonate pathway Simplified version of the steroid synthesis pathway with the intermediates isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), geranyl pyrophosphate (GPP) and squalene. Some intermediates are omitted. The color scheme does not correctly represent the origins of the isoprene units of GPP.
Printable version; In other projects ... Phosphomevalonic acid is an intermediate in the Mevalonate pathway. [1] Mevalonate pathway. (Phosphomevalonic acid labeled as ...
Mevalonate diphosphate decarboxylase catalyzes the final step in the mevalonate pathway. The mevalonate pathway is responsible for the biosynthesis of isoprenoids from acetate. [2] This pathway plays a key role in multiple cellular processes by synthesizing sterol isoprenoids, such as cholesterol, and non-sterol isoprenoids, such as dolichol ...
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2 comments Toggle Annotating the mevalonate pathway and usage in 3 articles subsection
Mevalonate pathway. In humans, cholesterol synthesis begins with the mevalonate pathway (see diagram), leading to the synthesis of farnesyl pyrophosphate (FPP). This pathway uses two acetyl-CoA and two NADPH to make mevalonate, which is metabolized to isopentenyl pyrophosphate (IPP) using three ATP. From there, three IPP are needed to make one FPP.