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Defensin, alpha 1 also known as human alpha defensin 1, human neutrophil peptide 1 (HNP-1) or neutrophil defensin 1 is a human protein that is encoded by the DEFA1 gene. [ 3 ] [ 4 ] [ 5 ] Human alpha defensin 1 belongs to the alpha defensin family of antimicrobial peptides .
Alpha defensins are a family of mammalian defensin peptides of the alpha subfamily. They are also known as cryptdins and are produced within the small bowel . Cryptdin is a portmanteau of crypt and defensin .
Defensin, alpha 1 Neutrophil defensin 1 Are expressed primarily in neutrophils as well as in NK cells and certain T-lymphocyte subsets. DEFA5 and DEFA6 are expressed in Paneth cells of the small intestine, where they may regulate and maintain microbial balance in the intestinal lumen. DEFA1B: Defensin, alpha 1B Defensin, alpha 1 DEFA3: Defensin ...
100041688 Ensembl ENSG00000164816 ENSG00000285251 ENSMUSG00000061845 UniProt Q01523 E9QLQ1 RefSeq (mRNA) NM_021010 NM_001177481 RefSeq (protein) NP_066290 NP_001170952 Location (UCSC) Chr 8: 7.06 – 7.06 Mb Chr 8: 21.56 – 21.56 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Defensin, alpha 5 (DEFA5) also known as human alpha defensin 5 (HD5) is a protein that in humans is encoded ...
This is a list of genes, proteins or receptors named A1 or Alpha-1 : Actin, alpha 1; Actinin, alpha 1; ... Cytochrome P450, family 1, member A1; Defensin, alpha 1;
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The principal defense molecules secreted by Paneth cells are alpha-defensins, which are known as cryptdins in mice. [13] These peptides have hydrophobic and positively charged domains that can interact with phospholipids in cell membranes. This structure allows defensins to insert into membranes, where they interact with one another to form ...
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