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The larger ovarian follicles consist of an external fibrovascular coat, connected with the surrounding stroma of the ovary by a network of blood vessels, and an internal coat, which consists of several layers of nucleated cells, called the membrana granulosa. It contains numerous granulosa cells.
The cumulus oophorus (discus proligerus) is a cluster of cells that surround the oocyte both in the ovarian follicle and after ovulation. In the antral follicle, it may be regarded as an extension of the membrana granulosa. The innermost layer of these cells is the corona radiata. [1]
Section of vesicular ovarian follicle of a cat. X 50. Membrana granulosa labeled at upper left. In the development of the urinary and reproductive organs, the oogonia become invaginated in the gonadal ridge. The embryological origin of granulosa cells remains controversial.
The best way to evaluate for an ovarian cyst is usually an ultrasound of the pelvis." Dr. Staci Tanouye , a board-certified ob-gyn, agrees, saying that most ovarian cysts don't cause symptoms.
Ovarian cysts may be classified according to whether they are a variant of the normal menstrual cycle, referred to as a functional or follicular cyst. [6] Ovarian cysts are considered large when they are over 5 cm and giant when they are over 15 cm. In children, ovarian cysts reaching above the level of the umbilicus are considered giant.
The outer layer is the ovarian cortex, consisting of ovarian follicles and stroma in between them. Included in the follicles are the cumulus oophorus , membrana granulosa (and the granulosa cells inside it), corona radiata , zona pellucida , and primary oocyte .