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  2. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Amyotrophic Lateral Sclerosis, Multiple Sclerosis Primary lateral sclerosis ( PLS ) is a very rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles . PLS belongs to a group of disorders known as motor neuron diseases .

  3. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or (in the United States) Lou Gehrig's disease (LGD), is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. [3]

  4. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    [1] [2] They include amyotrophic lateral sclerosis (ALS), [3] [4] progressive bulbar palsy (PBP), pseudobulbar palsy, progressive muscular atrophy (PMA), primary lateral sclerosis (PLS), spinal muscular atrophy (SMA) and monomelic amyotrophy (MMA), as well as some rarer variants resembling ALS. Motor neuron diseases affect both children and ...

  5. Latest Published 4 Rare Neurological Disorders Market Reports ...

    lite.aol.com/tech/story/0022/20250109/9327729.htm

    DelveInsight has recently released a series of epidemiology-based market reports on rare neurological disorders including Amyotrophic Lateral Sclerosis, Developmental and Epileptic Encephalopathies, Primary Ciliary Dyskinesia, and Chronic Inflammatory Demyelinating Polyneuropathy. These reports include a comprehensive understanding of current ...

  6. Neurodegenerative disease - Wikipedia

    en.wikipedia.org/wiki/Neurodegenerative_disease

    Amyotrophic lateral sclerosis (ALS), commonly referred to Lou Gehrig's disease, is a rare neurodegenerative disorder characterized by the gradual loss of both upper motor neurons (UMNs) and lower motor neurons (LMNs). [41] Although initial symptoms may vary, most patients develop skeletal muscle weakness that progresses to involve the entire ...

  7. Progressive muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Progressive_muscular_atrophy

    In contrast to amyotrophic lateral sclerosis or primary lateral sclerosis, PMA is distinguished by the absence of: [citation needed] brisk reflexes; spasticity; Babinski's sign; emotional lability; The importance of correctly recognizing progressive muscular atrophy as opposed to ALS is important for several reasons. The prognosis is a little ...

  8. Sclerosis (medicine) - Wikipedia

    en.wikipedia.org/wiki/Sclerosis_(medicine)

    Primary lateral sclerosis, progressive muscle weakness in the voluntary muscles. Primary sclerosing cholangitis, a hardening of the bile duct by scarring and repeated inflammation. Systemic sclerosis (progressive systemic scleroderma), a rare, chronic disease which affects the skin, and in some cases also blood vessels and internal organs.

  9. List of neurological conditions and disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_neurological...

    Lateral medullary (Wallenberg) syndrome; Learning disabilities; Leigh's disease; Lennox–Gastaut syndrome; Lesch–Nyhan syndrome; Leukodystrophy; Leukoencephalopathy with vanishing white matter; Lewy body dementia; Lissencephaly; Locked-in syndrome; Lou Gehrig's disease – see Amyotrophic lateral sclerosis; Lumbar disc disease; Lumbar hernia ...