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Imidazole is a planar 5-membered ring, that exists in two equivalent tautomeric forms because hydrogen can be bound to one or another nitrogen atom. Imidazole is a highly polar compound, as evidenced by its electric dipole moment of 3.67 D, [12] and is highly soluble in water.
2-Imidazoline (Preferred IUPAC name: 4,5-dihydro-1H-imidazole) is one of three isomers of the nitrogen-containing heterocycle imidazoline, with the formula C 3 H 6 N 2.The 2-imidazolines are the most common imidazolines commercially, as the ring exists in some natural products and some pharmaceuticals.
Purine is a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together.It is water-soluble.Purine also gives its name to the wider class of molecules, purines, which include substituted purines and their tautomers.
The numbering of ring atoms in azoles starts with the heteroatom that is not part of a double bond, and then proceeds towards the other heteroatom. Imidazole and other five-membered aromatic heterocyclic systems with two nitrogens are extremely common in nature and form the core of many biomolecules, such as histidine.
The enzyme purine imidazole-ring cyclase (EC 4.3.2.4) catalyzes the chemical reaction DNA 4,6-diamino-5-formamidopyrimidine ⇌ {\displaystyle \rightleftharpoons } DNA adenine + H 2 O This enzyme belongs to the family of lyases , specifically amidine lyases.
Histidine ball and stick model spinning. Histidine (symbol His or H) [2] is an essential amino acid that is used in the biosynthesis of proteins.It contains an α-amino group (which is in the protonated –NH 3 + form under biological conditions), a carboxylic acid group (which is in the deprotonated –COO − form under biological conditions), and an imidazole side chain (which is partially ...
In this drawing the imidazolone is the C 3 N 2 ring in red and black. [1] Imidazolinones or imidazolones are a family of heterocyclic compounds, the parents of which have the formula OC(NH) 2 (CH) 2. Two isomers are possible, depending on the location of the carbonyl (CO) group. The NH groups are nonadjacent.
In nature, imidazole alkaloids are found both as secondary plant compounds and as byproducts of histidine metabolism in marine organisms. One well-known imidazole alkaloid is pilocarpine , which is present in the leaves of Paraguay jaborandi .