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Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension . [ 2 ] While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.
Aliskiren/hydrochlorothiazide, sold under the brand name Tekturna HCT among others, is a fixed-dose combination medication for the treatment of hypertension ...
Aliskiren, the third-generation renin inhibitor. Aliskiren, an orally active non-peptide renin inhibitor, was the first drug in its class on the market. It is used to treat hypertension as monotherapy or in combination with other antihypertensive agents. [7] [39] The key to the discovery of aliskiren was crystallography and molecular modeling ...
Aspirin is an over-the-counter medication used for a variety of reasons, but particularly in heart attack and stroke prevention for older people. Dr. Michael J. Blaha, MD, ...
[1] [2] It contains aliskiren, a renin inhibitor; amlodipine, as the besylate, a calcium channel blocker; and hydrochlorothiazide, a thiazide diuretic. [1] It is taken by mouth. [1] It was approved for medical use in the United States in December 2010. [1] [3] [4] Amturnide was withdrawn by Novartis from the US market in 2017. [5]
Abbreviations are used in the list as follows: ... aliskiren ; alisporivir INN, USAN) alitretinoin ; alizapride ; Alka-Mints ; Alka-Seltzer ; Alkeran ...
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction.
The Kumada coupling is suitable for large-scale, industrial processes, such as drug synthesis. The reaction is used to construct the carbon skeleton of aliskiren (trade name Tekturna), a treatment for hypertension. [22] Kumada coupling in the synthesis of aliskiren