Ad
related to: gene splicing in humans process theory- Course Info
See Course Topics, Dates
Start Your Application
- Free Trial
Get A Free Preview
HMX Course Material
- About HMX
Unique Online Medical Courses
From Harvard Medical School
- Corporate Learning
Learn About Group Discounts.
Give Your Company An Edge.
- Course Info
Search results
Results From The WOW.Com Content Network
D-to-J recombination occurs first in the β-chain of the TCR. This process can involve either the joining of the D β 1 gene segment to one of six J β 1 segments or the joining of the D β 2 gene segment to one of six J β 2 segments. [3] DJ recombination is followed (as above) with V β-to-D β J β rearrangements.
Determining the complete set of components involved in splicing presents many challenges due to the abundance of alternative splicing, which occurs in most human genes, and the specificity in which splicing is carried out in vivo. [2] Splicing is distinctly conducted from cell type to cell type and across different stages of cellular development.
The split gene theory is a theory of the origin of introns, long non-coding sequences in eukaryotic genes between the exons. [1] [2] [3] The theory holds that the randomness of primordial DNA sequences would only permit small (< 600bp) open reading frames (ORFs), and that important intron structures and regulatory sequences are derived from stop codons.
A splice site mutation is a genetic mutation that inserts, deletes or changes a number of nucleotides in the specific site at which splicing takes place during the processing of precursor messenger RNA into mature messenger RNA. Splice site consensus sequences that drive exon recognition are located at the very termini of introns. [1]
It is a process through which two or more exons from different genes can be brought together ectopically, or the same exon can be duplicated, to create a new exon-intron structure. [1] There are different mechanisms through which exon shuffling occurs: transposon mediated exon shuffling, crossover during sexual recombination of parental genomes ...
Gene conversion is the process by which one DNA sequence replaces a homologous sequence such that the sequences become identical after the conversion. [1] Gene conversion can be either allelic, meaning that one allele of the same gene replaces another allele, or ectopic, meaning that one paralogous DNA sequence converts another.
Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single gene to produce different splice variants. For example, some exons of a gene may be included within or excluded from the final RNA product of the gene. [ 1 ]
Processing includes the addition of a 5' cap and a poly-A tail to the pre-mRNA chain, followed by splicing. Alternative splicing occurs when appropriate, increasing the diversity of the proteins that any single mRNA can produce. The product of the entire transcription process (that began with the production of the pre-mRNA chain) is a mature ...
Ad
related to: gene splicing in humans process theory