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A schematic for long bone endochondral ossification. In developing bones, ossification commences within the primary ossification center located in the center of the diaphysis (bone shaft), [5] where the following changes occur: The perichondrium surrounding the cartilage model transforms into the periosteum. During this transformation, special ...
Endocardial cushions, or atrioventricular cushions, refer to a subset of cells in the development of the heart that play a vital role in the proper formation of the heart septa. They develop on the atrioventricular canal [2] and conotruncal region of the bulbus cordis. [3] During heart development, the heart starts out as a tube. As heart ...
The Purkinje fibers, named for Jan Evangelista Purkyně, (English: / p ɜːr ˈ k ɪ n dʒ i / pur-KIN-jee; [1] Czech: [ˈpurkɪɲɛ] ⓘ; Purkinje tissue or subendocardial branches) are located in the inner ventricular walls of the heart, [2] just beneath the endocardium in a space called the subendocardium.
The bundle of His (BH) [1]: 58 or His bundle (HB) [1]: 232 (/ h ɪ s / "hiss" [2]) is a collection of heart muscle cells specialized for electrical conduction.As part of the electrical conduction system of the heart, it transmits the electrical impulses from the atrioventricular node (located between the atria and the ventricles) to the point of the apex of the fascicular branches via the ...
Diagram showing stages of endochondral ossification. Endochondral ossification is the formation of long bones and other bones. This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft).
The myocytes of the heart (also called the myocardial fibers) are arranged in a general circumferential direction in the ventricles. In the left ventricle (LV), the fiber will change gradually in direction from a certain longitudinal-circumferential direction in the outer layer of the heart (epicardium) to another angulated direction almost orthogonal in the inner wall (endocardium), becoming ...
The middle layer of the heart wall is the myocardium, which is the cardiac muscle—a layer of involuntary striated muscle tissue surrounded by a framework of collagen. The cardiac muscle pattern is elegant and complex, as the muscle cells swirl and spiral around the chambers of the heart, with the outer muscles forming a figure 8 pattern ...
As the relaxed ventricle fills during diastole, the walls are stretched and the length of sarcomeres increases. Sarcomere length can be approximated by the volume of the ventricle because each shape has a conserved surface-area-to-volume ratio. This is useful clinically because measuring the sarcomere length is destructive to heart tissue. It ...