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The 4Kscore combines total, free and intact PSA together with human kallikrein 2. [46] It is used to try to determine the risk of a Gleason score greater than 6. [46] The Prostate Health Index (PHI) is a PSA-based blood test for early prostate cancer screening. It may be used to determine when a biopsy is needed.
He was responsible for designing the algorithm [8] that is used in the commercial "4Kscore" test [9] for men with elevated PSA. With colleague Hans Lilja, Vickers published a series of studies demonstrating that a single PSA at age 45 - 60 is an extremely strong predictor of the long-term risk of prostate cancer mortality.
OPKO Health Announces Launch of 4Kscore™ in Europe Strategic Partner, International Health Technology Ltd, Launches Laboratory Service MIAMI--(BUSINESS WIRE)-- OPKO Health, Inc. (NYSE:OPK) today ...
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In practice, testing measures are never perfectly consistent. Theories of test reliability have been developed to estimate the effects of inconsistency on the accuracy of measurement. The basic starting point for almost all theories of test reliability is the idea that test scores reflect the influence of two sorts of factors: [7] 1.
The name of this formula stems from the fact that is the twentieth formula discussed in Kuder and Richardson's seminal paper on test reliability. [1] It is a special case of Cronbach's α, computed for dichotomous scores. [2] [3] It is often claimed that a high KR-20 coefficient (e.g., > 0.90) indicates a homogeneous test. However, like ...
Predicted reliability, ′, is estimated as: ′ = ′ + ′ where n is the number of "tests" combined (see below) and ′ is the reliability of the current "test". The formula predicts the reliability of a new test composed by replicating the current test n times (or, equivalently, creating a test with n parallel forms of the current exam).
The source reliability is rated between A (history of complete reliability) to E (history of invalid information), with F for source without sufficient history to establish reliability level. The information content is rated between 1 (confirmed) to 5 (improbable), with 6 for information whose reliability can not be evaluated.