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The prognosis of schizophrenia is varied at the individual level. In general it has great human and economics costs. [1] It results in a decreased life expectancy of 12–15 years primarily due to its association with obesity, little exercise, and smoking, while an increased rate of suicide plays a lesser role. [1]
By age and gender. Schizophrenia is diagnosed 1.4 times more frequently in males than females, and typically appears earlier in men [ 7 ] —the peak ages of onset are 20–28 years for males and 26–32 years for females. [ 9 ] Onset in childhood, before the age of 13 can sometimes occur. [ 10 ][ 11 ] A later onset can occur between the ages ...
Schizophrenia is a mental disorder [17][7] characterized by hallucinations (typically hearing voices), delusions, disorganized thinking and behavior, [10] and flat or inappropriate affect. [7] Symptoms develop gradually and typically begin during young adulthood and are never resolved. [3][10] There is no objective diagnostic test; diagnosis is ...
Sex differences in schizophrenia are widely reported. [1][2][3] Men and women exhibit different rates of incidence and prevalence, age at onset, symptom expression, course of illness, and response to treatment. [2][3][4] Reviews of the literature suggest that understanding the implications of sex differences on schizophrenia may help inform ...
Schizophrenia is a neurodevelopmental disorder with no precise or single cause. Schizophrenia is thought to arise from multiple mechanisms and complex gene–environment interactions with vulnerability factors. [1][2] Risk factors of schizophrenia have been identified and include genetic factors, environmental factors such as experiences in ...
The dopamine hypothesis of schizophrenia or the dopamine hypothesis of psychosis is a model that attributes the positive symptoms of schizophrenia to a disturbed and hyperactive dopaminergic signal transduction. The model draws evidence from the observation that a large number of antipsychotics have dopamine- receptor antagonistic effects.
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