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  2. Ezetimibe/simvastatin - Wikipedia

    en.wikipedia.org/wiki/Ezetimibe/simvastatin

    Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver. Simvastatin is an HMG-CoA reductase inhibitor or statin. It works by blocking an enzyme that

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    Furanocoumarins in grapefruit juice (i.e. bergamottin and dihydroxybergamottin) inhibit the cytochrome P450 enzyme CYP3A4, which is involved in the metabolism of most statins (however, it is a major inhibitor of only lovastatin, simvastatin, and to a lesser degree, atorvastatin) and some other medications [129] (flavonoids (i.e. naringin) were ...

  4. Atorvastatin - Wikipedia

    en.wikipedia.org/wiki/Atorvastatin

    Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [4] For the prevention of cardiovascular disease, statins are a first-line treatment. [4] It is taken by mouth. [4] Common side effects include joint pain, diarrhea, heartburn, nausea, and muscle pains. [4]

  5. Fewer people may need statins to prevent heart disease, new ...

    www.aol.com/news/fewer-people-may-statins...

    Statins, such as Lipitor, Crestor and Zocor, are widely used to protect against high levels of LDL cholesterol, one of the causes of cardiovascular disease. Doctors prescribe the daily pills based ...

  6. Pfizer Sues Merck to Block Lipitor/Zetia Combo Pill - AOL

    www.aol.com/2011/10/13/pfizer-sues-merck-to...

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  7. FDA Approves Powerful New Cholesterol Drug

    www.aol.com/news/2013-05-03-fda-approves...

    Merck gained Food and Drug Administration approval for its powerful new cholesterol drug Liptruzet, a combination of two already-approved drugs, Pfizer's Lipitor and Merck's Zetia. Merck already ...