Search results
Results From The WOW.Com Content Network
Classification and diagnosis of the underlying disease of hyperbilirubinemia are crucial for prescription of treatment. [6]Physical examination reviews clinical symptoms like degree of jaundice, vital signs and sensations of pain, further followed by urine tests, blood analysis and imaging.
Hyperbilirubinemia can cause a yellowing of the skin called jaundice depending on the level of bilirubin in the blood. [3] Additional symptoms of hyperbilirubinemia include darker urine (bilirubinuria) due to increased unconjugated bilirubin removed from the body in urine.
Neonatal jaundice spreads in a cephalocaudal pattern, affecting the face and neck before spreading down to the trunk and lower extremities in more severe cases. [51] Other symptoms may include drowsiness, poor feeding, and in severe cases, unconjugated bilirubin can cross the blood-brain barrier and cause permanent neurological damage ...
Rotor syndrome is a benign disease requiring no treatment. [2] Jaundice is a lifelong finding, but the disease is not associated with morbidity or mortality, and life expectancy is not affected. [2] Most individuals with Rotor syndrome are born to consanguineous couples and its diagnosis may coincidently identify consanguinity. [2]
Ritu Nahar, MD, a gastroenterologist with Allied Digestive Health, says symptoms of liver damage can include fatigue, jaundice, dark urine, pale stools, abdominal pain or swelling and unexplained ...
Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [1] Complications may include seizures, cerebral palsy, or kernicterus. [1] In most of cases there is no specific underlying physiologic disorder. [2]
Many people never have symptoms. [1] Occasionally jaundice (a slight yellowish color of the skin or whites of the eyes) may occur. [1] Gilbert syndrome is due to a genetic variant in the UGT1A1 gene which results in decreased activity of the bilirubin uridine diphosphate glucuronosyltransferase enzyme.
Dubin–Johnson syndrome is a benign condition and no treatment is required. However, it is important to recognize the condition so as not to confuse it with other hepatobiliary disorders associated with conjugated hyperbilirubinemia that require treatment or have a different prognosis. [8]