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Although recommended by treatment guidelines for the treatment of depression in bipolar disorder, the evidence that lithium is superior to placebo for acute depression is low-quality; [21] [22] atypical antipsychotics are considered more effective for treating acute depressive episodes. [23]
The American Psychiatric Association's DSM-5 Tooltip Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and the World Health Organization's ICD-10 Tooltip International Classification of Diseases (ICD-10), use the same criteria to diagnose bipolar disorder in adults and children with some adjustments to account for differences ...
The K-SADS-PL is used to screen for affective and psychotic disorders as well as other disorders, including, but not limited to Major Depressive Disorder, Mania, Bipolar Disorders, Schizophrenia, Schizoaffective Disorder, Generalized Anxiety, Obsessive Compulsive Disorder, Attention Deficit Hyperactivity Disorder, Conduct Disorder, Anorexia Nervosa, Bulimia, and Post-Traumatic Stress Disorder. [4]
Bipolar I disorder, most recent episode manic, in full remission: 296.45: Bipolar I disorder, most recent episode manic, in partial remission: 296.41: Bipolar I disorder, most recent episode manic, mild: 296.42: Bipolar I disorder, most recent episode manic, moderate: 296.44: Bipolar I disorder, most recent episode manic, severe with psychotic ...
Daily Assessment of Symptoms – Anxiety; Generalized Anxiety Disorder 7 (GAD-7) [4] [5] Hamilton Anxiety Scale (HAM-A) [6] [7] Hospital Anxiety and Depression Scale; Panic and Agoraphobia Scale (PAS) Panic Disorder Severity Scale (PDSS) PTSD Symptom Scale – Self-Report Version; Screen for child anxiety related disorders
People with bipolar disorder often have other co-existing psychiatric conditions such as anxiety (present in about 71% of people with bipolar disorder), substance abuse (56%), personality disorders (36%) and attention deficit hyperactivity disorder (10–20%) which can add to the burden of illness and worsen the prognosis. [24]
Mood stabilizers are often used as part of the treatment process. [17] Lithium is the mainstay in the management of bipolar disorder but it has a narrow therapeutic range and typically requires monitoring [18] Anticonvulsants, such as valproate, [19] carbamazepine, or lamotrigine
In a double-blind, placebo-controlled, proof-of-concept study, researchers administered an N-methyl-d-aspartate–receptor antagonist to 18 patients already on treatment with lithium (10 patients) or valproate (8 patients) for bipolar depression.