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Vitamin B 12 deficiency; Other names: Hypocobalaminemia, cobalamin deficiency: Image of the cervical spinal cord in vitamin B 12 deficiency showing subacute combined degeneration. . (A) The midsagittal T2 weighted image shows linear hyperintensity in the posterior portion of the cervical tract of the spinal cord (black arrow
Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.5–1.0 mg or more), [94] [95] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire ...
Animals, including humans, can convert cyanocobalamin to any one of the active vitamin B 12 compounds. [21] Cyanocobalamin is one of the most widely manufactured vitamers in the vitamin B 12 family (the family of chemicals that function as B 12 when put into the body), because cyanocobalamin is the most air-stable of the B 12 forms. [22]
Pernicious anemia is eventually treated with only injections of B 12; injections are typically 1 mg every other day, or twice weekly. A medical author takes the view that Mary Todd Lincoln, the wife of American President Abraham Lincoln, had pernicious anemia for decades and died from it in 1882. [77] [78]
[59] [11] [60] For example, for vitamin C, recommended intakes range from 40 mg/day in India [65] to 155 mg/day for the European Union. [66] The table below shows U.S. Estimated Average Requirements (EARs) and Recommended Dietary Allowances (RDAs) for vitamins, PRIs for the European Union (same concept as RDAs), followed by what three ...
US UL = 100 mg/day; EU UL = 25 mg/day: See Megavitamin-B 6 syndrome for more information. Vitamin B 7: None: No toxicity known. Folate 1 mg/day [26] Masks B 12 deficiency, which can lead to permanent neurological damage. [26] Vitamin B 12: None established [27] Skin and spinal lesions. Acne-like rash (causality is not conclusively established ...
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