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The IOP is higher during sleep. Efficacy of timolol in lowering IOP during the sleep period may be limited. [16] [17] [18] It is a 5–10× more potent beta blocker than propranolol. Timolol is light-sensitive; it is usually preserved with 0.01% benzalkonium chloride (BAC), but also comes BAC-free.
Side effects in less than 10% of people include other eye problems such as itching, foreign body sensation or dry eye, as headache or hyperpigmentation (darkening) of the skin around the eye. [ 4 ] Hyperpigmentation is an adverse effect of bimatoprost, [ 5 ] while the others are fairly common for eye drops in general.
Dorzolamide/timolol, sold under the brand name Cosopt among others, is a medication used to treat high pressure inside the eye including glaucoma. [3] [5] [6] It is a combination of dorzolamide hydrochloride and timolol maleate. [3] It may be used when a beta blocker, like timolol, is not sufficient alone. [7] It is used as an eye drop. [3]
A 12-week prospective, randomized, double-blinded study in 371 glaucoma and ocular hypertension patients with inadequate IOP control on monotherapy compared the efficacy and safety of 0.2% brimonidine tartrate/0.5% timolol fixed combination twice daily with the concomitant use of 0.2% brimonidine tartrate twice daily and timolol 0.5% twice ...
Eye drops: ATC code: S01ED51 ; Legal status; ... Travoprost/timolol, ... Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; ...
[4] [5] In rosacea it improves the redness. [5] It is used as eye drops or applied to the skin. [4] [5] It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate. [6] Common side effects when used in the eyes include itchiness, redness, and a dry mouth. [4]