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  2. Prader–Willi syndrome - Wikipedia

    en.wikipedia.org/wiki/PraderWilli_syndrome

    PraderWilli syndrome (PWS) is a rare genetic disorder caused by a loss of function of specific genes on chromosome 15. [2] In newborns, symptoms include weak muscles, poor feeding, and slow development. [2] Beginning in childhood, those affected become constantly hungry, which often leads to obesity and type 2 diabetes. [2]

  3. Chromosome 15 - Wikipedia

    en.wikipedia.org/wiki/Chromosome_15

    People normally have two copies of this chromosome in each cell, one copy from each parent. PraderWilli syndrome occurs when the paternal copy is partly or entirely missing. In about 70% of cases, [citation needed] PraderWilli syndrome occurs when the 15q11-q13 region of the paternal chromosome 15 is deleted. The genes in this region are ...

  4. What does growth hormone therapy treat? What an ... - AOL

    www.aol.com/does-growth-hormone-therapy-treat...

    Genetic conditions (including Turner Syndrome, Prader-Willi Syndrome, SHOX gene haploinsufficiency, and Noonan Syndrome) In adults, GH therapy has been FDA-approved to treat GHD and HIV-related ...

  5. Chromosomal deletion syndrome - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_deletion_syndrome

    PraderWilli (PWS) and Angelman syndrome (AS) are distinct neurogenetic disorders caused by chromosomal deletions, uniparental disomy or loss of the imprinted gene expression in the 15q11-q13 region. Whether an individual exhibits PWS or AS depends on if there is a lack of the paternally expressed gene to contribute to the region.

  6. Urban–Rogers–Meyer syndrome - Wikipedia

    en.wikipedia.org/wiki/Urban–Rogers–Meyer...

    Urban–Rogers–Meyer syndrome, also known as PraderWilli habitus, osteopenia, and camptodactyly or Urban syndrome, [1] is an extremely rare inherited congenital disorder first described by Urban et al. (1979).

  7. The touching story behind this 7-year-old social media star's ...

    www.aol.com/news/touching-story-behind-7-old...

    Ryan's sister Sarah, who died in 2011, had cerebral palsy, which made it difficult for her to walk, and Prader-Willi syndrome, a genetic disorder that involves intellectual disability and causes ...

  8. Uniparental disomy - Wikipedia

    en.wikipedia.org/wiki/Uniparental_disomy

    The most well-known conditions include PraderWilli syndrome and Angelman syndrome. Both of these disorders can be caused by UPD or other errors in imprinting involving genes on the long arm of chromosome 15. [6]

  9. We all need HGH, the hormone responsible for growth. What ...

    www.aol.com/hgh-hormone-responsible-growth...

    In adults, HGH helps regulate blood glucose levels, she adds. Is HGH legal? ... SHOX gene haploinsufficiency, Noonan Syndrome and Prader Willi Syndrome, says O’Sullivan. ...