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In the late 2000s, two of Huffman's cannabinoid compounds were found in street drugs K2 and Spice being sold in Germany as marijuana alternatives. "I figured once it got started in Germany it was going to spread. I'm concerned that it could hurt people," Huffman said. "I think this was something that was more or less inevitable.
K 2 is both a tissue and bacterial product (derived from vitamin K 1 in both cases) and is usually found in animal products or fermented foods. [1] The number n of isoprenyl units in their side chain differs and ranges from 4 to 13, hence vitamin K 2 consists of various forms. [2] It is indicated as a suffix (-n), e. g. MK-7 or MK-9.
Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. [1] The human body requires vitamin K for post-synthesis modification of certain proteins that are required for blood coagulation ("K" from Danish koagulation, for "coagulation") or for controlling binding of calcium in bones and other tissues. [2]
As an example of its accuracy, 18th century scientist Guillaume Le Gentil, during a visit to Pondicherry, India, found the Indian computations (based on Aryabhata's computational paradigm) of the duration of the lunar eclipse of 30 August 1765 to be short by 41 seconds, whereas his charts (by Tobias Mayer, 1752) were long by 68 seconds.
The name K2 is derived from the notation used by the Great Trigonometrical Survey of British India. Thomas Montgomerie made the first survey of the Karakoram from Mount Haramukh, some 210 km (130 mi) to the south, and sketched the two most prominent peaks, labeling them K1 and K2, where the K stands for Karakoram. [21]
Basal, undivergent K2a* (K-M2308*) has been found only in the remains of two Upper Paleolithic individuals, known as "Ust'-Ishim man and "Oase-1", [3] who lived in Siberia and the Banat region of south-central Europe, respectively, about 37–45 ky BP. No examples of K-M2313* or NO1* (NO-M214*) have been identified in living males or remains.
K are found in all potassium, and it is the most common radioisotope in the human body. Potassium ions are vital for the functioning of all living cells. The transfer of potassium ions across nerve cell membranes is necessary for normal nerve transmission; potassium deficiency and excess can each result in numerous signs and symptoms, including ...
A suitable route up the Abruzzi Ridge had been explored in detail, good sites for tents had been found (sites that would go on to be used in many future expeditions) and they had identified the technically most difficult part of the climb, up the House Chimney at 22,000 feet (6,700 m) (named after Bill House who had led the four-hour climb up ...