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Benign symmetric lipomatosis, also known as Madelung's disease, is an adult-onset skin condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. [1] The symmetrical fat deposits are made of unencapsulated lipomas , which distinguishes it from typical lipomatosis which has encapsulated lipomas that ...
Swelling of the legs, with possible discolouration of the skin (darkening or reddening). Swelling and discolouration is most prominent towards the direction of gravity (foot/ankle when standing). Depending on severity, the calf and thigh may appear swollen. Skin conditions can develop such as venous ulcers, lipodermatosclerosis, and stasis ...
The management of lipodermatosclerosis may include treating venous insufficiency with leg elevation and elastic compression stockings. [9] In some difficult cases, the condition may be improved with the additional use of the fibrinolytic agent, stanozol. Fibrinolytic agents use an enzymatic action to help dissolve blood clots.
Lymphedema, also known as lymphoedema and lymphatic edema, is a condition of localized swelling caused by a compromised lymphatic system. [2] The lymphatic system functions as a critical portion of the body's immune system and returns interstitial fluid to the bloodstream.
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Individuals affected by RS3PE typically have repeated episodes of inflammation of the lining of their synovial joints and swelling of the end portion of the limbs. [8] The arms and hands are more commonly affected than the legs and feet. [8] Both sides are usually involved though RS3PE can affect only one side in certain cases. [8]