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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
An orally disintegrating tablet or orally dissolving tablet (ODT) is a drug dosage form available for a limited range of over-the-counter (OTC) and prescription medications. ODTs differ from traditional tablets in that they are designed to be dissolved on the tongue rather than swallowed whole.
“Zofran is an anti-nausea medication,” says Qing, and it’s typically used preventatively. Zofran is an antiemetic that works by blocking the chemical that causes nausea and vomiting, per the ...
Benefits are greater if used before the onset of symptoms or shortly after symptoms begin. [2] Side effects, however, may limit the use of medications. [3] A number of medications used for nausea such as ondansetron and metoclopramide are not effective in motion sickness. [3] [2]
Preliminary clinical data suggests ginger may be effective for treatment of nausea and/or vomiting in a number of settings. [19] [20] [21] Emetrol is also claimed to be an effective antiemetic. Propofol is given intravenously. It has been used in an acute care setting in hospital as a rescue therapy for emesis. [22]
Several treatment methods are available to help prevent CINV. Pharmaceutical treatment is generally separated into two types: prophylactic (preventative) treatment, given before the dose of chemotherapy agents, and rescue treatment, given to treat breakthrough nausea and vomiting.
5-HT 3 antagonists are most effective in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV), especially that caused by highly emetogenic drugs such as cisplatin; when used for this purpose, they may be given alone or, more frequently, with a glucocorticoid, usually dexamethasone.
Nausea and or vomiting is the main complaint in 1.6% of visits to family physicians in Australia. [6] However, only 25% of people with nausea visit their family physician. [1] In Australia, nausea, as opposed to vomiting, occurs most frequently in persons aged 15–24 years, and is less common in other age groups. [6]