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Basic structure of a peroxisome Distribution of peroxisomes (white) in HEK 293 cells during mitosis Peroxisome in rat neonatal cardiomyocyte. A peroxisome (/ p ə ˈ r ɒ k s ɪ ˌ s oʊ m /) [1] is a membrane-bound organelle, a type of microbody, found in the cytoplasm of virtually all eukaryotic cells. [2] [3] Peroxisomes are oxidative ...
A peroxisome is a type of microbody that functions to help the body break down large molecules and detoxify hazardous substances. It contains enzymes like oxidase, react hydrogen peroxide as a byproduct of its enzymatic reactions. Within the peroxisome, hydrogen peroxide can then be converted to water by enzymes like catalase and peroxidase.
224824 Ensembl ENSG00000124587 ENSMUSG00000002763 UniProt Q13608 Q99LC9 RefSeq (mRNA) NM_000287 NM_001316313 NM_145488 RefSeq (protein) NP_000278 NP_001303242 NP_663463 Location (UCSC) Chr 6: 42.96 – 42.98 Mb Chr 17: 47.02 – 47.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Peroxisome assembly factor 2 is a protein that in humans is encoded by the PEX6 gene. PEX6 is an AAA ...
Lysosomes and peroxisomes: Lysosomes contain digestive enzymes (acid hydrolases). They digest excess or worn-out organelles , food particles, and engulfed viruses or bacteria . Peroxisomes have enzymes that rid the cell of toxic peroxides , Lysosomes are optimally active in an acidic environment.
The peroxisome is an organelle in the cell similar to the lysosome that functions to detoxify the cell. Peroxisomes contain many different enzymes, such as catalase, and their main function is to neutralize free radicals and detoxify drugs. For this reason peroxisomes are ubiquitous in the liver and kidney.
Peroxisomal targeting signal 1 receptor (PTS1R) is a protein that in humans is encoded by the PEX5 gene. [5]PTS1R is a peroxisomal targeting sequence involved in the specific transport of molecules for oxidation inside the peroxisome.
The glycosomes are the most divergent of the different types of organelles stemming from peroxisomes, especially as seen in the trypanosomes. Peroxisomes of higher eukaryotes are very similar to the glycosomes and the glyoxysomes that are found in some plants and fungi. The glycosome shares the same basic level structure of a single membrane ...
Peroxisomal disorders represent a class of medical conditions caused by defects in peroxisome functions. [1] This may be due to defects in single enzymes [2] important for peroxisome function or in peroxins, proteins encoded by PEX genes that are critical for normal peroxisome assembly and biogenesis.