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The Canadian formulation of Preparation H includes a yeast extract called Biodyne which was removed in 1995 from the formulation sold in the United States. This yeast extract was the primary ingredient of the original formulation by inventor George Sperti , [ 5 ] [ 6 ] and Pfizer believes that it removes wrinkles from skin and heals dry ...
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George Speri Sperti (January 17, 1900, Covington, Kentucky – April 29, 1991, Cincinnati, Ohio) was an Italian-American who invented Preparation H hemorrhoid medication. He also invented the Sperti Ultraviolet Lamp, Aspercreme for pain relief, and KVa Power Meter. [1] [2] Sperti graduated from the University of Cincinnati in 1923. Shortly ...
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
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Topical delivery is often used for drugs that are easily degraded in the GI tract, or are highly susceptible to hepatic first pass effect. [ 1 ] [ 2 ] Even if the drug has to be administered for long periods of time or can induce adverse drug reactions in parts of the body other than the target location, it can still be formulated as a topical gel.
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