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c. 2,200 per year (U.S.) [8] Alcohol intoxication, also known in overdose as alcohol poisoning, [1] commonly described as drunkenness or inebriation, [9] is the behavior and physical effects caused by a recent consumption of alcohol. [6][10] In addition to the toxicity of ethanol, the main psychoactive component of alcoholic beverages, other ...
Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. [8] It has also been found effective in the treatment of other addictions and may be used for them off-label. [12]
Most overdoses occur when drugs are ingested in combination with alcohol. [32] Drug overdose was the leading cause of injury death in 2013. Among people 25 to 64 years old, drug overdose caused more deaths than motor vehicle traffic crashes. There were 43,982 drug overdose deaths in the United States in 2013.
Use of opioid overdose antidote by laypersons rose 43% from 2020 to 2022, study finds. Naloxone, best known by the brand name Narcan, became available over the counter last fall. After years of ...
Naloxone is useful in treating both acute opioid overdose and respiratory or mental depression due to opioids. [13] Whether it is useful in those in cardiac arrest due to an opioid overdose is unclear. [21] It is included as a part of emergency overdose response kits distributed to heroin and other opioid drug users, and to emergency responders.
Fomepizole is used to treat ethylene glycol and methanol poisoning. It acts to inhibit the breakdown of these toxins into their active toxic metabolites. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase, [ 6 ] found in the liver. This enzyme plays a key role in the metabolism of ethylene glycol, and of methanol.
A coma cocktail is a combination of substances administered in an emergency to comatose individuals when the cause of the coma has not yet been determined. [1] The intention is to work against various causes of a coma seen in an emergency setting including drug overdoses and hypoglycemia. The coma cocktail is sometimes colloquially referred to ...
Antidote. An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton), " (medicine) given as a remedy". Antidotes for anticoagulants are sometimes referred to as reversal agents.