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Nifedipine, sold under the brand name Procardia among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. [2] It is one of the treatments of choice for Prinzmetal angina . [ 2 ]
Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain , heart failure and esophageal spasms. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. [2] It is taken by mouth. [2]
A 20% lipid emulsion commonly used for calcium channel blocker toxicity: Specialty: Emergency medicine: Symptoms: Slow heart rate, low blood pressure, nausea, vomiting, sleepiness [1] [2] Complications: Cardiac arrest [2] Usual onset: Within 6 hours [2] Causes: Too much calcium channel blockers either by accident or on purpose [3] Differential ...
Nisoldipine is a pharmaceutical drug used for the treatment of chronic angina pectoris and hypertension. It is a calcium channel blocker of the dihydropyridine class. It is sold in the United States under the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels. [1] It was patented in 1975 and approved for medical use in ...
Felodipine is metabolized by cytochrome P450 3A4, so substances that inhibit or activate CYP3A4 can strongly effect how much felodipine is present. [1]CYP3A4 inhibitors, which increase the amount of felodipine available per dose, include cimetidine, erythromycin, itraconazole, ketoconazole, HIV protease inhibitors, and grapefruit juice.
The regular dosage is 60 mg tablets every four hours. If the patient is unable to take tablets orally, it was previously given via intravenous infusion at a rate of 1–2 mg/hour (lower dosage if the body weight is <70 kg or blood pressure is too low), [7] but since the withdrawal of the IV preparation, administration by nasogastric tube is an alternative.
Nitrendipine is given to hypertensive individuals in 20 mg oral tablets every day. [3] This amount is effective in reducing blood pressure by 15–20% within 1–2 hours of administration. [3]
Lercanidipine is used in form of the hydrochloride, [4] which is a slightly yellow crystalline powder and melts at 197 to 201 °C (387 to 394 °F) in crystal form I or 207 to 211 °C (405 to 412 °F) in crystal form II. [10] It is readily soluble in chloroform and methanol, but practically insoluble in water. [11]