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Tissue hypoxia from low oxygen delivery may be due to low haemoglobin concentration (anaemic hypoxia), low cardiac output (stagnant hypoxia) or low haemoglobin saturation (hypoxic hypoxia). [79] The consequence of oxygen deprivation in tissues is a switch to anaerobic metabolism at the cellular level.
Generalized hypoxia is a medical condition in which the tissues of the body are deprived of the necessary levels of oxygen due to an insufficient supply of oxygen, which may be due to the composition or pressure of the breathing gas, decreased lung ventilation, or respiratory disease, any of which may cause a lower than normal oxygen content in the arterial blood, and consequently a reduced ...
Tissue hypoxia refers to low levels of oxygen in the tissues of the body and the term hypoxia is a general term for low levels of oxygen. [2] Hypoxemia is usually caused by pulmonary disease whereas tissue oxygenation requires additionally adequate circulation of blood and perfusion of tissue to meet metabolic demands. [4]
A well-known symptom of the coronavirus is low oxygen levels in the body, aka hypoxia, which normally lead to shortness of breath. The phenomenon is referred to as "silent" or "happy hypoxia ...
During a stroke, there is an interruption in the blood supply followed by reperfusion which leads to histotoxic hypoxia because of an accumulation of reactive oxygen species (ROS). [4] In the case of inflammatory diseases, histotoxic hypoxia can also be triggered by ROS from mitochondrial damage in the active lesions of chronic multiple sclerosis.
The main reason for the acute phase of ischemia-reperfusion injury is oxygen deprivation and, therefore, arrest of generation of ATP (cellular energy currency) by mitochondria oxidative phosphorylation. Tissue damage due to the general energy deficit during ischemia is followed by reperfusion (increase of oxygen level) when the injury is enhanced.
Cerebral hypoxia is a form of hypoxia ... Prolonged hypoxia induces neuronal cell death via ... Severe asthma exacerbations may also lead to symptoms of hypoxic hypoxia.
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