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The therapeutic recommended dosages were 12.5, 25, and 50 mg with an approximate bioavailability of 93%. [12] [13] [14] Rofecoxib crossed the placenta and blood–brain barrier, [12] [13] [15] and took 1–3 hours to reach peak plasma concentration with an effective half-life (based on steady-state levels) around 17 hours.
Pharmaceutical powerhouse Merck (NYS: MRK) has agreed to settle a class action lawsuit filed in Missouri by Vioxx customers, the company announced yesterday. Those who filed the lawsuit had ...
In 2005, Lanier represented Carol Ernst in a lawsuit against Merck & Co., a pharmaceutical company and manufacturer of Vioxx, an anti-inflammatory drug used to treat osteoarthritis and acute pain conditions. Ernst was married to Robert Ernst, a former marathon runner who died after taking the medication.
Zocor, Vioxx, Pepsid: False Claims Act, Medicaid Rebate Statute 2007 Purdue Pharma [15] $601 million Off-label promotion Oxycontin: False Claims Act 2010 Allergan [16] $600 million Off-label promotion Botox: False Claims Act, FDCA 2010 AstraZeneca [17] $520 million Off-label promotion, kickbacks Seroquel: False Claims Act 2007 Bristol-Myers ...
Merck & Co.'s Vioxx Recall. Cost: $6.4 billion. ... The company lost an estimated $725 million in sales and ended up paying out billions in lawsuits. In 2008, Merck settled most of its product ...
About 50,000 people sued Merck, claiming they or their family members had suffered medical problems such as heart attacks or strokes after taking Vioxx. [172] In November 2007, Merck agreed to pay $4.85 billion to settle most of the pending Vioxx lawsuits. [173]
In 2008, Seeger was a lead negotiator in the $4.85 billion Vioxx settlement on behalf of plaintiffs. [9] Seeger was one of the first lawyers to file a Vioxx-related injury lawsuit against Merck. [10] In 2009, Seeger represented homeowners who had defective Chinese-manufactured drywall installed in their homes.
Members of the family who own OxyContin maker Purdue Pharma, and the company itself, agreed to pay up to $7.4 billion in a new settlement to lawsuits over the toll of the powerful prescription ...