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Influential factors include the THC dose, the person’s body fat, sex, how hydrated they are, recent exercise and their metabolism rate, according to Medical News Today.
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Anxiety and depression have been found to increase susceptibility to marijuana use. [52] This is due to a desire to alleviate the symptoms of these experiences through marijuana use. Chronic users who use for anxiolytic purposes will even develop dependencies on cannabis, making it difficult to cope with anxiety when the drug is absent.
[64] 11-OH-THC is the first metabolic product in this pathway. Both Delta-9-THC and 11-OH-THC are psychoactive. The metabolism of THC into 11-OH-THC plays a part in the heightened psychoactive effects of edible cannabis. [65] Next, 11-OH-THC is metabolized in the liver into 11-COOH-THC, which is the second metabolic product of THC.
That said, research has shown that marijuana may slightly increase testosterone levels which may be associated with increased acne, says dermatologist Karan Lal, MD. When your testosterone spikes ...
When marijuana's active ingredient, THC, hits the brain, it causes brain cells to release the feel-good chemical dopamine. Dopamine is a part of the brain's reward system — it's the same ...
However, everyday use of cannabis may be correlated with psychological withdrawal symptoms, such as irritability or insomnia, [105] and susceptibility to a panic attack may increase as levels of THC metabolites rise. [110] [111] Cannabis withdrawal symptoms are typically mild and are not life-threatening. [112]
The metabolism of those with type 1 or type 2 diabetes will be different, attributed to the insulin resistance and potential metabolic syndrome.Because diabetes impairs the body’s ability to ...