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Those affected by schizophrenia are also more inclined to develop numerous physiological and psychological conditions. Most notably, they experience higher rates of substance abuse and suicidality; where more than half of people with schizophrenia have reported suicide ideation or attempts, and nearly half experience substance abuse or dependence. [19]
There is a higher than average suicide rate associated with schizophrenia estimated at 5% to 6%, most often occurring in the period following onset or first hospital admission. [ 18 ] [ 28 ] Several times more (20 to 40%) attempt suicide at least once.
Schizophrenia is a somewhat rare disease affecting approximately 3.2 million Americans in the United States. Also, in an average year, about 100,000 individuals will be diagnosed with schizophrenia. [18] In 2010, there were approximately 397,200 hospitalizations for schizophrenia in the United States.
Typical antipsychotics have equal drop-out and symptom relapse rates to atypicals when used at low to moderate dosages. [138] There is a good response in 40–50%, a partial response in 30–40%, and treatment resistance (failure of symptoms to respond satisfactorily after six weeks to two or three different antipsychotics) in 20% of people. [139]
The average volumetric changes in these studies are however close to the limit of detection by MRI methods, so it remains to be determined whether schizophrenia is a neurodegenerative process that begins at about the time of symptom onset, or whether it is better characterised as a neurodevelopmental process that produces abnormal brain volumes ...
Schizophreniform disorder is a type of mental illness that is characterized by psychosis and closely related to schizophrenia.Both schizophrenia and schizophreniform disorder, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), have the same symptoms and essential features except for two differences: the level of functional impairment and the duration of symptoms.
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