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Phentermine is used for a short period of time to promote weight loss, if exercise and calorie reduction are not sufficient, and in addition to exercise and calorie reduction. [5] [15] Phentermine is approved for up to 12 weeks of use and most weight loss occurs in the first weeks. [15]
Weight loss in those receiving the fen-phen combination was significantly greater (8.4±1.1 kg) than in those receiving placebo (4.4±0.9 kg) and equivalent to that of those receiving fenfluramine (7.5±1.2 kg) or phentermine alone (10.0±1.2 kg). This amounts to an additional weight loss of 4±2 kg over the course of 24 weeks.
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
Liraglutide Weight Loss Injections. Liraglutide is the active ingredient in Saxenda and Victoza. Like Ozempic and Wegovy, liraglutide is an injected GLP-1 receptor agonist that can suppress ...
If less than 3% weight loss is seen after 3 months it is recommended the medication be stopped. [3] The weight loss is modest. [ 3 ] Effects on heart related health problems or death is unclear.
Phenmetrazine has been used as an appetite suppressant for purposes of weight loss. [2] It was used therapeutically for this indication at a dosage of 25 mg two or three times per day (or 50–75 mg/day total) in adults. [2] Phenmetrazine has been found to produce similar weight loss to dextroamphetamine in people with obesity. [3]
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