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  2. Innovative Genomics Institute - Wikipedia

    en.wikipedia.org/wiki/Innovative_Genomics_Institute

    The IGI sustainable agriculture program and its Plant Genomics and Transformation Facility has developed CRISPR protocols for editing over 30 common crop species, [17] and has worked on developing applications including protecting the world's chocolate supply from cacao swollen shoot virus, [55] [56] removing toxic cyanide precursors in cassava ...

  3. Yield10 Bioscience - Wikipedia

    en.wikipedia.org/wiki/Yield10_Bioscience

    Yield10 has also commenced development of CRISPR-enabled technology to impact crop yield. The company received a nonregulated status letter from the USDA-APHIS Biotechnology Regulatory Services (BRS) acknowledging that its camelina line has had a gene disrupted using CRISPR/Cas9 gene editing technology, resulting in the desired phenotype.

  4. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.

  5. Illumina, CRISPR-pioneer Broad Institute to work on new gene ...

    www.aol.com/news/illumina-crispr-pioneer-broad...

    Illumina's partnership with Massachusetts-based Broad Institute - one of the most prominent names in CRISPR research - aims to use a new method called PerturbSeq screening for scaling up gene ...

  6. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR-Cas9. CRISPR gene editing (CRISPR, pronounced / ˈ k r ɪ s p ə r / (crisper), refers to a clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified.

  7. CRISPR activation - Wikipedia

    en.wikipedia.org/wiki/CRISPR_activation

    See: Guide RNA, CRISPR. Complementary base pairing between the sgRNA and genomic DNA allows targeting of Cas9 or dCas9. A small guide RNA (sgRNA), or gRNA is an RNA with around 20 nucleotides used to direct Cas9 or dCas9 to their targets. gRNAs contain two major regions of importance for CRISPR systems: the scaffold and spacer regions.

  8. Precision BioSciences - Wikipedia

    en.wikipedia.org/wiki/Precision_BioSciences

    Precision is in the process of developing multiple candidates targeting non-Hodgkin lymphoma, acute lymphoblastic leukemia (ALL), [4] [19] and multiple myeloma. [23] The company's lead candidate targeting CD19, PBCAR0191, [19] received orphan drug designation from the U.S. Food and Drug Administration for the treatment of ALL and mantle cell lymphoma, an aggressive subtype of non-Hodgkin ...

  9. Agricultural biotechnology - Wikipedia

    en.wikipedia.org/wiki/Agricultural_biotechnology

    Farmers have manipulated plants and animals through selective breeding for decades of thousands of years in order to create desired traits. In the 20th century, a surge in technology resulted in an increase in agricultural biotechnology through the selection of traits like the increased yield, pest resistance, drought resistance, and herbicide resistance.