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Flunarizine is a selective calcium antagonist with moderate other actions including antihistamine, serotonin receptor blocking and dopamine D 2 blocking activity. Compared to other calcium channel blockers such as dihydropyridine derivatives, verapamil and diltiazem, flunarizine has low affinity to voltage-dependent calcium channels.
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [3] Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3]
Macular hard drusen in the right eye. 65-year-old diabetic woman. Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with ...
Paradoxically, when pilocarpine induces this ciliary muscle contraction (known as an accommodative spasm) it causes the eye's lens to thicken and move forward within the eye. This movement causes the iris (which is located immediately in front of the lens) to also move forward, narrowing the Anterior chamber angle .
All cycloplegics are also mydriatic (pupil dilating) agents and are used as such during eye examination to better visualize the retina. When cycloplegic drugs are used as a mydriatic to dilate the pupil, the pupil in the normal eye regains its function when the drugs are metabolized or carried away.
The management of strabismus may include the use of drugs or surgery to correct the strabismus.Agents used include paralytic agents such as botox used on extraocular muscles, [1] topical autonomic nervous system agents to alter the refractive index in the eyes, and agents that act in the central nervous system to correct amblyopia.
Drugs such as tropicamide are used in medicine to permit examination of the retina and other deep structures of the eye. Mydriatics typically also have a cycloplegic effect, reducing or paralyzing the accommodation reflex which may also be used for certain ophthalmic examinations or treatments, such as reducing painful ciliary muscle spasm .
Particularly when associated with dry eyes, blepharospasm may be relieved with warm compresses, eye drops, and eye wipes. [40] [41] A Japanese study showed that warm compresses containing menthol were more effective in increasing tear film. [42] Drugs used to treat blepharospasm are anticholinergics, benzodiazepines, baclofen, and tetrabenazine ...