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Monosaccharide color code in the Symbol Nomenclature For Glycans (SNFG) The Symbol Nomenclature For Glycans (SNFG) [1] is a community-curated standard for the depiction of simple monosaccharides and complex carbohydrates using various colored-coded, geometric shapes, along with defined text additions. [2] [3] It is hosted by the National Center ...
Glycan nomenclature is the systematic naming of glycans, which are carbohydrate-based polymers made by all living organisms. In general glycans can be represented in (i) text formats, these include commonly used CarbBank, IUPAC name, and several other types; and (ii) symbol formats, these are consisting of Symbol Nomenclature For Glycans and Oxford Notations.
Another nomenclature uses the systematic name of the molecular graph, a ' D-' or ' L-' prefix to indicate the position of the last chiral hydroxyl on the Fischer diagram (as above), and another italic prefix to indicate the positions of the remaining hydroxyls relative to the first one, read from bottom to top in the diagram, skipping the keto ...
In molecular biology and biochemistry, glycoconjugates are the classification family for carbohydrates – referred to as glycans – which are covalently linked with chemical species such as proteins, peptides, lipids, and other compounds. [1] Glycoconjugates are formed in processes termed glycosylation.
N-Linked glycans are attached in the endoplasmic reticulum to the nitrogen (N) in the side chain of asparagine (Asn) in the sequon.The sequon is an Asn-X-Ser or Asn-X-Thr sequence, where X is any amino acid except proline and the glycan may be composed of N-acetylgalactosamine, galactose, neuraminic acid, N-acetylglucosamine, fucose, mannose, and other monosaccharides.
In contrast, the oligosaccharides themselves are often referred to as paucimannosidic, low mannose, and truncated glycans or other less conventional nomenclature. [4] A simple shorthand nomenclature has been proposed as a convenient way to name the individual paucimannosidic glycan structures, e.g. M3F denotes Man 3 GlcNAc 2 Fuc 1. [6] [7] [8] [9]
Vendor Glycoconjugates, Glycan Recognizing Proteins; The Functional Glycomics Gateway. monthly updated web resource, a collaboration of Nature and the Consortium for Functional Glycomics. Carolyn Bertozzi's Seminar: "Chemical Glycobiology" Emanual Maverakis; et al. "Glycans in the immune system and The Altered Glycan Theory of Autoimmunity" (PDF).
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