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Mott cells with Russell bodies (red arrows), compared to an almost normal plasma cell (white arrow; it has a prominent nucleolus). Plasmacytoma with abundant Russell bodies. H&E stain. Dutcher and Russell bodies. H&E stain. Russell bodies are inclusion bodies usually found in atypical plasma cells that become known as Mott cells. [1]
The table shown on the right can be used in a two-sample t-test to estimate the sample sizes of an experimental group and a control group that are of equal size, that is, the total number of individuals in the trial is twice that of the number given, and the desired significance level is 0.05. [4]
Example: To find 0.69, one would look down the rows to find 0.6 and then across the columns to 0.09 which would yield a probability of 0.25490 for a cumulative from mean table or 0.75490 from a cumulative table. To find a negative value such as -0.83, one could use a cumulative table for negative z-values [3] which yield a probability of 0.20327.
Plasma cells with Dutcher and Russell bodies (H&E stain, 100×, oil) Plasma cells are large lymphocytes with abundant cytoplasm and a characteristic appearance on light microscopy . They have basophilic cytoplasm and an eccentric nucleus with heterochromatin in a characteristic cartwheel or clock face arrangement.
[15] [16] But if the p-value of an observed effect is less than (or equal to) the significance level, an investigator may conclude that the effect reflects the characteristics of the whole population, [1] thereby rejecting the null hypothesis. [17] This technique for testing the statistical significance of results was developed in the early ...
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Exact tests that are based on discrete test statistics may be conservative, indicating that the actual rejection rate lies below the nominal significance level . As an example, this is the case for Fisher's exact test and its more powerful alternative, Boschloo's test. If the test statistic is continuous, it will reach the significance level ...
Many test statistics, scores, and estimators encountered in practice contain sums of certain random variables in them, and even more estimators can be represented as sums of random variables through the use of influence functions. The central limit theorem implies that those statistical parameters will have asymptotically normal distributions.