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In clinical practice, post-test probabilities are often just estimated or even guessed. This is usually acceptable in the finding of a pathognomonic sign or symptom, in which case it is almost certain that the target condition is present; or in the absence of finding a sine qua non sign or symptom, in which case it is almost certain that the target condition is absent.
Example Questions S Site Where is the pain? Or the maximal site of the pain. O Onset When did the pain start, and was it sudden or gradual? Include also whether it is progressive or regressive. C Character What is the pain like? An ache? Stabbing? R Radiation: Does the pain radiate anywhere? A Associations Any other signs or symptoms associated ...