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Type 1 is caused by a mutation in the PAX3 gene, while the gene that most often causes type 2 when mutated is MITF. [1] [7] Type 3 is a more severe presentation of type 1 and is caused by a mutation in the same gene, while type 4 is most often caused by a mutation in SOX10.
Piebaldism is unrelated to conditions such as vitiligo or poliosis. Although "partial albinism" is a synonym for piebaldism, [ 3 ] it is a fundamentally different condition from true albinism . The vision problems associated with albinism are not usually present as eye pigmentation is normal.
Some genetic conditions that result in a "leucistic" appearance include piebaldism, Waardenburg syndrome, vitiligo, Chédiak–Higashi syndrome, flavism, isabellinism, xanthochromism, axanthism, amelanism, and melanophilin mutations. Pale patches of skin, feathers, or fur (often referred to as "depigmentation") can also result from injury.
These photos beautifully capture how vitiligo has made Buster even more unique: November 2021, November 2022, August 2023, and April 2024. Image credits: TallyMatty Audio isn’t the first cat to ...
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Vitiligo is a condition that causes the skin to begin to lose its pigmentation—or color—for no apparent reason, resulting in white patches that are especially noticeable in people whose skin ...
Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy ...
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