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It is also being used in pre-workout and bodybuilding supplements with claims of a stimulant effect. [4] There is also evidence suggesting that N,N-DMPEA acts as a TAAR1 agonist in humans, [5] and as a 5-HT1A ligand in rats.
GNC Holdings, LLC (an initialism of General Nutrition Centers) is an American multinational retail and nutritional manufacturing company based in Pittsburgh, Pennsylvania. [5] [6] It specializes in health and nutrition related products, including vitamins, supplements, minerals, herbs, sports nutrition, diet, and energy products.
Pre-workout supplements contain a variety of ingredients such as caffeine and creatine, differing by capsule or powder products. [2] [3] The first pre-workout product entered the market in 1982, and since then the category has grown in use. [4] Some pre-workout products contain ingredients linked to adverse effects. [2]
Methylhexanamine (also known as methylhexamine, 1,3-dimethylamylamine, 1,3-DMAA, dimethylamylamine, and DMAA; trade names Forthane and Geranamine) is an indirect sympathomimetic drug invented and developed by Eli Lilly and Company and marketed as an inhaled nasal decongestant from 1948 until it was voluntarily withdrawn from the market in the 1980s.
The company launched its first carbonated pre-workout energy drink in 2018, called C4 On The Go Carbonated. [10] In 2021, Cellucor partnered with Mars Incorporated to bring flavors based on Starburst and Skittles to the C4 line. [11] [12] In March 2022, C4 became the official energy drink of SXSW. [13]
Energy drinks generally contain methylxanthines (including caffeine), B vitamins, carbonated water, and high-fructose corn syrup or sugar (for non-diet versions). Other common ingredients are guarana , yerba mate , açaí , and taurine , plus various forms of ginseng , maltodextrin , inositol , carnitine , creatine , glucuronolactone ...
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