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Opsoclonus myoclonus syndrome (OMS), also known as opsoclonus-myoclonus-ataxia (OMA), is a rare neurological disorder of unknown cause which appears to be the result of an autoimmune process involving the nervous system. It is an extremely rare condition, affecting as few as 1 in 10,000,000 people per year.
Possible causes of opsoclonus include neuroblastoma and encephalitis in children, and breast, lung, or ovarian cancer in adults. Other considerations include GLUT1 Deficiency Syndrome , multiple sclerosis , toxins, medication effects (e.g. Serotonin Syndrome ), celiac disease , certain infections ( West Nile virus , Lyme disease ), non-Hodgkin ...
Kinsbourne was the first to identify and systematically describe the infant disorder "opsoclonus myoclonus" syndrome, sometimes called Kinsbourne syndrome in his honor. He also was first to describe "hiatus hernia" with contortions of the neck, subsequently called Sandifer Syndrome in honor of his mentor, Dr. Paul Sandifer.
As with adults, anti-Hu encephalitis is associated with malignancy. The cancers most associated with anti-Hu encephalitis are neuroblastoma and ganglioneuroblastoma. Opsoclonus-myoclonus syndrome (OMS) is a condition that develops in children as a result of anti-Hu antibodies. The illness afflicts younger children, with one study showing an age ...
Opsoclonus myoclonus syndrome: Central nervous system, eye movement control Anti-neuronal antibodies Possible [105] Optic neuritis: Optic nerve Various Confirmed [106] Scleritis: Sclera: Various Possible [107] Susac's syndrome: Retina, cochlea, and brain None specific Probable [108] Sympathetic ophthalmia: Uveal tract: Various Probable Rare [109]
CKM syndrome, a cluster of conditions that may lead to heart disease, may affect 90% of U.S. adults. Doctors explain cardiovascular-kidney-metabolic syndrome.
Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle, a joint, or a group of muscles, different from clonus, which is rhythmic or regular. Myoclonus (myo-"muscle", clonus "spasm") describes a medical sign and, generally, is not a diagnosis of a disease.
A new study finds that 9 out of 10 adults in the U.S. may have cardiovascular-kidney-metabolic (CKM) syndrome. The research found 90% of adults qualify for stage 1 or higher of this condition.