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Tianeptine, sold under the brand names Stablon, Tatinol, and Coaxil among others, is an atypical tricyclic antidepressant which is used mainly in the treatment of major depressive disorder, although it may also be used to treat anxiety, asthma, and irritable bowel syndrome.
Watson and Clark (1991) proposed the Tripartite Model of Anxiety and Depression to help explain the comorbidity between anxious and depressive symptoms and disorders. [1] This model divides the symptoms of anxiety and depression into three groups: negative affect, positive affect and physiological hyperarousal.
Anxiety is an emotion characterised by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events. [1] [2] [3] Anxiety is different from fear in that fear is defined as the emotional response to a present threat, whereas anxiety is the anticipation of a future one. [4]
The term depression was derived from the Latin verb deprimere, "to press down". [80] From the 14th century, "to depress" meant to subjugate or to bring down in spirits. It was used in 1665 in English author Richard Baker's Chronicle to refer to someone having "a great depression of spirit", and by English author Samuel Johnson in a similar ...
"Depression with anxious distress" was added into the DSM-5 as a means to emphasize the common co-occurrence between depression or mania and anxiety, as well as the risk of suicide of depressed individuals with anxiety. Specifying in such a way can also help with the prognosis of those diagnosed with a depressive or bipolar disorder.
The 11th revision of the International Classification of Diseases (ICD-11) defines dysphoria as "an unpleasant mood state, which can include feelings of depression, anxiety, discontent, irritability, and unhappiness." [2] Dissatisfaction with being able-bodied can be diagnosed as body integrity dysphoria in the ICD-11. [3]
Anxiety disorders affect nearly 30% of adults at some point in their lives, with an estimated 4% of the global population currently experiencing an anxiety disorder. However, anxiety disorders are treatable, and a number of effective treatments are available. [11] Most people are able to lead normal, productive lives with some form of treatment ...
For example, when the brain lacks serotonin, a chemical that regulates the brain's functioning, it can lead to depression, appetite changes, aggression, and anxiety. Another cause of mental distress can be exposure to severely distressing life-threatening situations and experiences.