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The oxygen enhancement ratio (OER) or oxygen enhancement effect in radiobiology refers to the enhancement of therapeutic or detrimental effect of ionizing radiation due to the presence of oxygen. This so-called oxygen effect [ 1 ] is most notable when cells are exposed to an ionizing radiation dose .
The best known explanation of the oxygen effect is the oxygen fixation hypothesis developed by Alexander in 1962, [9] which posited that radiation-induced non-restorable or "fixed" nuclear DNA lesions are lethal to cells in the presence of diatomic oxygen. [10] [11] Recent hypotheses include one based on oxygen-enhanced damage from first ...
As ions' damage is direct, OER (Oxygen Enhancement Ratio) is 1, so the effect of oxygen it is not important. An important approach of hypoxia-related treatment interventions is a procedure called dose painting, in which a higher radiation dose is targeted to hypoxic subvolumes of tumor. [ 37 ]
Oxygen enhancement ratio, effect magnitude of ionizing radiation due to the presence of oxygen; Oxygen Evolution Reaction, the formation of oxygen by electrochemical reduction of water; Owner’s Equivalent Rent, an economic metric for housing prices often used in the calculation of market baskets
With a normal P a O 2 of 60–100 mmHg and an oxygen content of F I O 2 of 0.21 of room air, a normal P a O 2 /F I O 2 ratio ranges between 300 and 500 mmHg. A P a O 2 /F I O 2 ratio less than or equal to 200 mmHg is necessary for the diagnosis of acute respiratory distress syndrome by the AECC criteria. [7]
An arterial blood gas (ABG) test, or arterial blood gas analysis (ABGA) measures the amounts of arterial gases, such as oxygen and carbon dioxide.An ABG test requires that a small volume of blood be drawn from the radial artery with a syringe and a thin needle, [1] but sometimes the femoral artery in the groin or another site is used.
As a result, the brain adapts to the challenge of reading. The process of reading involves most of the brain, especially an interconnection between visual areas and language areas; but also neural systems related to action, emotion, decision-making, and memory. [2] [3] The science of reading (SOR) is the discipline that studies reading. [4]
Reading is the process of taking in the sense or meaning of symbols, often specifically those of a written language, by means of sight or touch. [1] [2] [3] [4]For educators and researchers, reading is a multifaceted process involving such areas as word recognition, orthography (spelling), alphabetics, phonics, phonemic awareness, vocabulary, comprehension, fluency, and motivation.