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  2. Thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Thrombocythemia

    Often, it occurs in tandem with an inflammatory disease as the principal stimulants of platelet production (e.g. thrombopoietin) are elevated in these clinical states as part of the acute phase reaction. High platelet counts can occur in patients with polycythemia vera (high red blood cell counts), and is an additional risk factor for ...

  3. Essential thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Essential_thrombocythemia

    Hydroxycarbamide, interferon-α and anagrelide can lower the platelet count. Low-dose aspirin is used to reduce the risk of blood clot formation unless the platelet count is very high, where there is a risk of bleeding from the disease, and hence this measure would be counter-productive as aspirin-use increases the risk of bleeding. [3] [15 ...

  4. Mean platelet volume - Wikipedia

    en.wikipedia.org/wiki/Mean_platelet_volume

    An increased mean platelet volume (MPV) increases the risk to suffer a heart disease [2] MPV may be higher when there is destruction of platelets. This may be seen in immune thrombocytopenic purpura (ITP), myeloproliferative diseases and Bernard–Soulier syndrome. It may also be related to pre-eclampsia and recovery from transient hypoplasia. [3]

  5. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause . Recurrent thrombosis: Hemophilia: Hemophilia A: Hemophilia B: Hemophilia C: Von Willebrand disease: Antiphospholipid syndrome: Thrombocytopenia: Glanzmann's thrombasthenia: Wiskott–Aldrich syndrome

  6. Giant platelet disorder - Wikipedia

    en.wikipedia.org/wiki/Giant_platelet_disorder

    Giant platelet disorder; Two giant platelets (stained purple) are visible in this image from a light microscope (40×) from a peripheral blood smear surrounded by red blood cells. One normal platelet can be seen in the upper left side of the image (purple) and is significantly smaller in size than the red blood cells (stained pink). Specialty ...

  7. Myelodysplastic syndrome - Wikipedia

    en.wikipedia.org/wiki/Myelodysplastic_syndrome

    Typically seen in older women with normal or high platelet counts and isolated deletions of the long arm of chromosome 5 in bone marrow cells. Myelodysplasia unclassifiable Seen in those cases of megakaryocyte dysplasia with fibrosis and others. Refractory cytopenia of childhood (dysplasia in childhood) –

  8. Disseminated intravascular coagulation - Wikipedia

    en.wikipedia.org/wiki/Disseminated_intravascular...

    A rapidly declining platelet count; High levels of fibrin degradation products, including D-dimer, are found owing to the intense fibrinolytic activity stimulated by the presence of fibrin in the circulation. The peripheral blood smear may show fragmented red blood cells (known as schistocytes) due to shear stress from thrombi. However, this ...

  9. Thrombopoietin - Wikipedia

    en.wikipedia.org/wiki/Thrombopoietin

    Thrombopoietin is a glycoprotein hormone produced by the liver and kidney which regulates the production of platelets. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. [5] Megakaryocytopoiesis is the cellular development process that leads to platelet production.